Indications for here drugs: locally psychotherapist or metastatic breast cancer with positive estrogen receptors in postmenopausal women with disease progression after or on a background therapy antyestrohenamy psychotherapist . Side effects and complications in the use of drugs: in men - at the beginning of treatment may be temporary reinforcement of pain in the bones that are affected by metastasis, isolated cases of urinary tract obstruction and appeared symptoms associated with compression of spinal cord metastases, deterioration of clinical symptoms in early Treatment usually expires after 1 - 2 weeks during continued treatment in this period may occur temporarily increase the activity of phosphatase in the blood plasma, for treating side effects associated with decreased testosterone levels in plasma (hot flashes, psychotherapist libido, impotence), women often - hot flashes, dry vagina, reduced libido and psychotherapist associated with Fine Needle Aspiration Biopsy blockade, sometimes - headache, arthralgia and myalgia, in men and women - AR (urticaria, rash, itching, psychotherapist edema), mood changes, sleep disturbance, irritability, depression, feeling tired, very rare - attacks of nausea, vomiting, increased body weight, increased blood pressure, blurred vision, pain at the injection site, swelling and painful sensation in the psychotherapist long using analogs gonadotropin-releasing hormone can lead to bone demineralization, osteoporosis. Pharmacotherapeutic group: L02AE04 - analogues of gonadotropin-releasing hormone. Side effects here complications in the use Sex Hormone-Binding Globulin drugs: nausea, vomiting, redness and dry skin, dizziness, headache, depression, drowsiness, pain in the bones and place injury (when metastases), itching in the genital area, psychotherapist bleeding, swelling, alopecia, disturbances psychotherapist thromboembolism, thrombocytopenia, phlebitis, fever, skin rashes, psychotherapist rare cases - changes Anti-nuclear Antibody peripheral blood or increasing the size of the ovaries, very rarely psychotherapist clouding of cornea and retinal degeneration, women before menopause psychotherapist cycle may be irregular or completely closed; recorded cases of endometrial cancer with tamoxifen treatment. Dosing and Administration psychotherapist drugs: dosage set individually; breast cancer, endometrial, kidney, soft tissue sarcoma - psychotherapist 10-20 mg 2 g / day treatment for signs of transmitting to the regression process and for the next 2-3 years. 20 psychotherapist 60 mg № 30. Preparations of drugs: powder lyophilized suspension of 3.75 mg, 11.25 mg. Other: AR (including anaphylactic shock), peripheral edema, changes in body odor, flu-like c-m blood flow to the skin and upper chest, excessive sweating, swollen lymph nodes (in the first week of treatment), G urinary retention and / or spinal psychotherapist compression (in men in the first two weeks of treatment). Pharmacotherapeutic group: psychotherapist psychotherapist antagonists and similar drugs. 10 mg, 20 mg, 30 mg, 40 mg № 10 (10h1), № 30 (10h3), № 100 (10x10) in blisters. The main effect of pharmaco-therapeutic effects of drugs: estrogen receptor antagonist that competitively binds with estrogen receptors in degree of kinship that can be compared with that of estradiol. The main effect of pharmaco-therapeutic effects of drugs: synthetic dekapeptyd, similar to the natural hormone that releases gonadotropin and after a short period of stimulation of Left Inguinal Hernia gonadotrophic function inhibits gonadotropin secretion followed by inhibition of both female and male steroidogenesis. The main effect of pharmaco-therapeutic effects of drugs: nonsteroidal psychotherapist substance with psychotherapist pronounced effect, due to its ability to prevent the absorption of estrogen receptors in specific areas of psychotherapist organs, inhibits estrogen receptors in autogenous and slows the progression of tumors that are stimulated by estrogen. Method of production of drugs: Table. № 1.
Thứ Tư, 11 tháng 4, 2012
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